Happens again on me now.
I start DF and it direktly goes to max out my CPU, here is the debuginfo:

***** Machine **********************************************
Operating System: Microsoft Windows NT 6.1.7600.0 (6.1.7600.0)
Detected Version: Windows7 / Server2008R2 (Windows7 / Server2008R2)
CPU: x64
Date/Time (UTC): 04/08/2010 21:21:04
Date/Time (Local): 04/08/2010 23:21:04
.NET Framework: 2.0.50727.4927
CurrentCulture: German (Germany) (de-DE ~ de)
CurrentUICulture: German (Germany) (de-DE ~ de)
On Battery: No

***** Wallpaper ****************************************
Active Desktop: False
Wallpaper Span: True
Spanned Image: C:\Users\Mumpi\Pictures\Backgrounds\hiddenforces12x3360.jpg (Exists: True)
Windows Wallpaper: C:\Users\Mumpi\AppData\Roaming\DisplayFusion\Wallpaper_2.jpg (Exists: True)
Generated Wallpaper Folder: C:\Users\Mumpi\AppData\Roaming\DisplayFusion

***** DisplayFusion ************************************
Name: DisplayFusion Pro v3.1.8
Build Date: Mrz 17, 2010 18:17
Pro: True
License Key: 921be876b1060dba7636a2f08ac68993
Command Line: "C:\Program Files (x86)\DisplayFusion\DisplayFusion.exe"
Current Folder: C:\Program Files (x86)\DisplayFusion
Performance Mode: False
Application Hooks: True
System Hooks Pause FullScreen: False
Process Integrity Level: High
Font Scaling: 1

***** Themes *******************************************
Visual Styles: True
Visual Styles Detected: True
DWM Composition Detected: True
Filename: C:\Windows\resources\Themes\Aero\Aero.msstyles
Colour: NormalColor
Size: NormalSize
File: --
Bitmap File: --

***** Monitor 3 (Primary:True ~ Real:True) *************
Name: \\.\DISPLAY3
Bounds: {X=0,Y=0,Width=1920,Height=1080}
WorkArea: {X=0,Y=0,Width=1920,Height=1050}

***** Monitor 4 (Primary:False ~ Real:True) ************
Name: \\.\DISPLAY4
Bounds: {X=-1920,Y=0,Width=1920,Height=1080}
WorkArea: {X=-1920,Y=0,Width=1920,Height=1050}

***** Monitors by Bounds *******************************
4, 3
Force Order: None

***** Screens ******************************************
Count: 2
Point Min: {X=-1920,Y=0}
Point Max: {X=1920,Y=1080}
Total Size: {Width=3840, Height=1080}
ActiveDesktop: False

***** Screen 1 *****************************************
ScreenID: 2
Device: \\.\DISPLAY3
Bounds: {X=0,Y=0,Width=1920,Height=1080}
MoveH: 0
MoveV: 0
Scaling: 100%

***** Screen 2 *****************************************
ScreenID: 3
Device: \\.\DISPLAY4
Bounds: {X=-1920,Y=0,Width=1920,Height=1080}
MoveH: 0
MoveV: 0
Scaling: 100%

***** FullScreen Applications **************************
None

***** Compatibility ************************************
None

***** Taskbars *****************************************
Enabled: True
Taskbar Mode: ShowRelevant
Middle-Click Behaviour: OpenNewInstance
Button Style: IconsAndText
Auto-hide: False
Opacity: 100
Flash Blink: False
Thumbnail Preview: True
Thumbnail Preview Animations: True
Sizing Bar Size: 0
Button Width Max: 160
Button Width Override: 0
Button Icon Size: 16
Colour Tracking Override: None
Button Height: 30
Text Glow Size: 0
Count: 1

***** Taskbar 1 ****************************************
Location: {X=-1920,Y=1050,Width=1920,Height=30}
Monitor ID: 4
Position (Setting/Current): Automatic / Bottom
Size: Automatic
TopMost: True
Buttons (2):
"Elisa" ~ Handles:01a507ce:01a507ce:01a507ce ~ ImageType:Unknown ~ NormalIcon:None ~ LargeIcon:None ~ Exception:None ~ WindowPosition:{X=-1634,Y=193,Width=653,Height=724}
"TweetDeck" ~ Handles:000806c8:000806c8:000806c8 ~ ImageType:GCL_HIconSM ~ NormalIcon:{Width=32, Height=32} ~ LargeIcon:{Width=32, Height=32} ~ Exception:None ~ WindowPosition:{X=-1928,Y=-8,Width=1936,Height=1066}

***** Taskbar Deleted Items (2) ************************
01a507ce:01a507ce:01a507ce
000806c8:000806c8:000806c8

***** Taskbar Items ************************************
"DisplayFusion Pro ~ Einstellungen" (000608d2:000608d2:000608d2 ~ None ~ {X=557,Y=243,Width=807,Height=565})
"DisplayFusion Pro ~ Hintergrundbild" (000304c0:000304c0:000304c0 ~ None ~ {X=553,Y=179,Width=815,Height=693})
"Process Explorer - Sysinternals: www.sysinternals.com [Mumpitz\Mumpi]" (00080324:00080324:00080324 ~ None ~ {X=-8,Y=-8,Width=1936,Height=1066})
"Elisa" (01a507ce:01a507ce:01a507ce ~ None ~ {X=-1634,Y=193,Width=653,Height=724})
"TweetDeck" (000806c8:000806c8:000806c8 ~ None ~ {X=-1928,Y=-8,Width=1936,Height=1066})
"" (000103ea:000103ea:000103ea ~ DelphiUnknown ~ {X=960,Y=540,Width=0,Height=0})
"JDownloader" (000403be:000403be:000403be ~ None ~ {X=440,Y=225,Width=800,Height=600})
"Season 2 Episode Guide on TV.com - Mozilla Firefox" (000105bc:000105bc:000105bc ~ None ~ {X=365,Y=0,Width=783,Height=750})
"led plate of ambient beats and grooves. [SomaFM]) - Winamp *** 1. Jens Buchert - Sanso Sheep (Groov" (0004050c:0004050c:0004050c ~ Winamp ~ {X=498,Y=497,Width=275,Height=116})

***** TitleBar Buttons *********************************
Enabled: False
DisplayFusion Caption Button Size: {Width=31, Height=17}
System Caption Button Size: {Width=35, Height=21}
Detected Caption Button Size: {Width=31, Height=17}
Custom Background: None

***** HotKeys ******************************************
"Bewege Fenster auf nächsten Bildschirm" ~ CTRL;WIN;88 ~ Windows Aero\Next Monitor.png
"Bewege Fenster auf nächsten Bildschirm und maximiere es" ~ CTRL;WIN;65 ~
"Bewege Fenster auf nächsten Bildschirm und passe Größe proportional an" ~ CTRL;WIN;90 ~
"Bewege Fenster auf vorherigen Bildschirm" ~ CTRL;WIN;87 ~
"Bewege Fenster auf vorherigen Bildschirm und maximiere es" ~ CTRL;WIN;69 ~
"Bewege Fenster auf vorherigen Bildschirm und passe Größe proportional an" ~ CTRL;WIN;68 ~
"Dehne das Fenster auf alle Bildschirme aus" ~ CTRL;WIN;192 ~
"Fensterleisten-Symbole umschalten" ~ * ~
"Mehrfach-Taskleise umschalten" ~ * ~
"Passe die Größe des Fensters an und bewege es auf dem Bildschirm nach links" ~ CTRL;WIN;37 ~
"Passe die Größe des Fensters an und bewege es auf dem Bildschirm nach oben" ~ CTRL;WIN;38 ~
"Passe die Größe des Fensters an und bewege es auf dem Bildschirm nach rechts" ~ CTRL;WIN;39 ~
"Passe die Größe des Fensters an und bewege es auf dem Bildschirm nach unten" ~ CTRL;WIN;40 ~
"Steuerungs-Fenster immer im Vordergrund" ~ * ~
"Tastaturkürzel EIn/Aus" ~ * ~
"Wechsle zum nächsten Hintergrundbild (nur Pro-Version)" ~ CTRL;WIN;82 ~
"Zentriere Fenster auf Bildschirm und setze Größe auf 75%" ~ CTRL;WIN;83 ~
"Zentriere Fenster auf dem Bildschirm" ~ CTRL;WIN;81 ~

***** DisplayFusion ************************************
Path: C:\Program Files (x86)\DisplayFusion\DisplayFusion.exe
Name: DisplayFusion
Prod Version: 3.1.8.0
File Version: 3.1.8.0
Size: 800.944 bytes
Date Modified (UTC): Mrz 17, 2010 @ 17:17

***** DisplayFusion x86 Hook DLL ***********************
Path: C:\Program Files (x86)\DisplayFusion\DisplayFusionHookx86.dll
Name: DisplayFusion Hook
Prod Version: 2, 4, 0, 0
File Version: 2, 4, 0, 0
Size: 48.304 bytes
Date Modified (UTC): Dez 09, 2009 @ 14:08

***** DisplayFusion x64 Hook DLL ***********************
Path: C:\Program Files (x86)\DisplayFusion\DisplayFusionHookx64.dll
Name: DisplayFusion Hook
Prod Version: 2, 4, 0, 0
File Version: 2, 4, 0, 0
Size: 46.768 bytes
Date Modified (UTC): Dez 09, 2009 @ 14:08

***** DisplayFusion x86 Hook ***************************
Path: C:\Program Files (x86)\DisplayFusion\DisplayFusionHookx86.exe
Name: DisplayFusion Hook x86
Prod Version: 1, 8, 0, 0
File Version: 1, 8, 0, 0
Size: 92.848 bytes
Date Modified (UTC): Dez 13, 2009 @ 20:23

***** Managed Threads **********************************
Count: 9
ID:3 ~ Name:TaskbarManager ~ Age:00:00:34.8979961 ~ Alive:True ~ BG:True ~ State:Background ~ Thread Name:TaskbarManager_ac8ae4f8-08d1-44e0-bebc-ac83eb19de6a
ID:4 ~ Name:HookManager ~ Age:00:00:34.8949959 ~ Alive:True ~ BG:True ~ State:Background ~ Thread Name:HookManager_d04406eb-887f-4f51-ba1d-9c03e71987f0
ID:6 ~ Name:HookManagerProcess ~ Age:00:00:34.8709945 ~ Alive:True ~ BG:True ~ State:Background ~ Thread Name:HookManagerProcess_770c5535-6d98-4870-a0ca-e8005d16d6c7
ID:44 ~ Name:TaskbarButtonUpdate (Update) ~ Age:00:00:04.0642324 ~ Alive:True ~ BG:True ~ State:Background ~ Thread Name:TaskbarButtonUpdate (Update)_dd7f32d7-8b2c-4857-b4dd-35297121227b
ID:38 ~ Name:TaskbarButtonUpdate (Replace Null) ~ Age:00:00:03.4301962 ~ Alive:True ~ BG:True ~ State:Background ~ Thread Name:TaskbarButtonUpdate (Replace Null)_ef4fb4ba-5aac-479f-b8f1-fc888e774410
ID:29 ~ Name:TaskbarButtonUpdate (Replace Null) ~ Age:00:00:02.5271445 ~ Alive:True ~ BG:True ~ State:Background ~ Thread Name:TaskbarButtonUpdate (Replace Null)_a6e04c62-90f6-40a0-b93d-45dd5d8f1262
ID:11 ~ Name:TaskbarButtonUpdate (Replace Null) ~ Age:00:00:02.0121151 ~ Alive:True ~ BG:True ~ State:Background ~ Thread Name:TaskbarButtonUpdate (Replace Null)_198c16e1-8f07-4d80-918f-1d25fb550c26
ID:28 ~ Name:TaskbarButtonUpdate (Update) ~ Age:00:00:01.4040803 ~ Alive:True ~ BG:True ~ State:Background ~ Thread Name:TaskbarButtonUpdate (Update)_8874653c-6b4a-49f9-8bc5-ee9481f4ff5c
ID:24 ~ Name:TaskbarButtonUpdate (Update) ~ Age:00:00:00.6550374 ~ Alive:True ~ BG:True ~ State:Background ~ Thread Name:TaskbarButtonUpdate (Update)_5c8e0e16-4a59-4319-93c3-d54c2a3fb758

***** Processes ****************************************
Cache Items: 3