EDIT: Changing the DP port on the graphics card seems to have resolved the issue, but will leave below in the event there's additional insight.

On the latest DF, have tried disabling taskbar options and application hooks already.

Whenever I attempt to set the refresh rate of my main display back to 144Hz, the screen flashes black and then stays black (as if not connected, no signal to monitor).

Before DF, I ran this gsync monitor at 144Hz (Dell SG2716DG via DP from NVIDIA 980 Ti). Looking to see if this may be a Windows issue or a DF issue.

Note: I have 3 monitors total (Main display is the GSync - connected to DP, a second monitor (not high refresh rate - also DP, which I frequently will turn off when just needing one monitor), and a TV connected via HDMI for certain games (the profile used will disable main monitor, use second DP as a "secondary" and the HDMI will become the primary).