I saw a similar issue reported already but I dont think its the same, at least I cant seem to replicate the issue doing what he is describing.

When im gaming on certain games, some windows will come to the front out of nowhere, it might be that Im clicking on the apps on the taskbar even if its not there, or it might not, im not sure because trying to do it on purpose doesnt work, it just happens randomly, the issue gets fixed as soon as I close DP, so I'm certain its the culprit. I have a DP taskbar on the screen I game, in the past I used the windows one (and kept DP to secondary screens) and I didnt have an issue.
On one of the clips I see the little preview that you get when you mouse over the taskbar apps, on the other clip the app literally just came to the front.

I'm on the latest beta, however this occurred on the current non beta version as well. I'm on Win 11 (I used win10 with no issues until 2 weeks ago and upgraded)
My task bar is on the right side of the screen

Some gifs showing the issue:
https://i.imgur.com/RAxc33e.gif
https://i.imgur.com/khRy4OD.gif

This issue has happened on games such as Dead by Daylight, Valorant, and most recently Battlefield 6 that I can recall of, doesnt happen in every game I play (might be caused by borderless windows, mouse movements and click combinations, however trying to replicate this intentionally hasnt worked for me)

I'm going to try the workaround posted by the person on the other post, turning off "Focus window when mouse is dragged over Taskbar button", however I believe this is something that should be fixed on DPs end, I cant add every game I play to some list because I play countless when I stream.

Cheers and I hope you can detect whats causing this.