I use display fusion to switch between my triple monitors (for sim racing) and my two desk monitors (used for work, internet, etc). I typically load up a race on my lunch break (switch from my desktop profile to my triple monitor profile) and it seems that 10 minutes after switching profiles, my active monitors will go black and my inactive monitors will refresh as if it is search for a signal. After a couple of seconds, the picture returns to normal on my triple monitors and all is well. However, this always happens in the middle of my gameplay and 10 minutes is long enough to get in the middle of a race and screw me up every time. I thought this was a game issue or an nvidia issue but this occurs on completely separate computers and different games.

is this a windows thing or perhaps a displayfusion thing? Anyone else have ideas?

So I switched profiles (from my desktop profile to the triple profile) and immediately exited Display fusion. Still had the same problem so I guess this must be a windows/Nvidia issue :/