This might be an obvious answer, or not feasible.

In my attached monitor set up, is there a setting that would allow the mouse to jump from the left corner of monitor three, to monitor 1?

I can shift monitor 3 to the left, so that it touches the border of monitor 1, to make that work. However, when the mouse goes from 2 to 3, or 3 to 2, it's off by 3-4" and that drives me crazy.