Windows 10 (and I guess 11) supports the creation of multiple "desktops" through the "task view" button on the task bar.
Assuming I have set up two (or more) virtual "desktops" in this fashion, is there any way to get the triggers to manipulate windows on a PARTICULAR virtual desktop? (note this is not the same as multiple monitors as each desktop would share the same current monitor profile)
DisplayFusion doesn't currently support virtual desktop specific functions, but it's planned for a future version. I've added your info to the open feature request for that.