Thanks for the heads up! This is due to the fact that the hotkeys can be setup on the Functions tab as well, but that doesn't update if it's set somewhere else (like the Manage Monitor Profiles window) while the Settings window is open. So when you click ok, the settings get overwritten with the old ones (no hotkeys assigned).
Long story short, I have an idea on how we can resolve this, and I've put it on our list to investigate further :)
Thanks!